Hepatotoxicity of Halogenated Inhalational Anesthetics

Hepatotoxicity of Halogenated Inhalational Anesthetics

CONTEXT Halogenated inhalational anesthetics are currently the most common drugs used for the induction and maintenance of general anesthesia. Postoperative hepatic injury has been reported after exposure to these agents. Based on much evidence, mechanism of liver toxicity is more likely to be immunoallergic. The objective of this review study was to assess available studies on hepatotoxicity o...

hepatotoxicity of halogenated inhalational anesthetics

conclusions hepatotoxicity of halogenated inhalational anesthetics has been well documented in available literature. halothane-induced liver injury was extensively acknowledged; however, the next generation halogenated anesthetics have different molecular structures and associated with less hepatotoxicity. although anesthesia-induced hepatitis is not a common occurrence, we must consider the as...

Halogenated Anesthetics and Human Myocardium

THE effects of halogenated anesthetics on the myocardium have been studied extensively in vivo and in vitro in various animal species. In the past, investigators have focused their efforts on heart function, myocardial mechanics, and electrophysiology. During recent years, considerable knowledge has been obtained by new investigative methodologies, including molecular and cellular biology and a...

Modern inhalational anesthetics for refractory status epilepticus.

BACKGROUND Our goal was to perform a systematic review of the literature on the use of modern inhalational anesthetic agents for refractory status epilepticus and their impact on seizure control. METHODS All articles from MEDLINE, BIOSIS, EMBASE, Global Health, HealthStar, Scopus, Cochrane Library, the International Clinical Trials Registry Platform (inception to March 2014), reference lists ...

Nephrotoxicity of halogenated inhalational anaesthetics: fictions and facts.